Conclusion作者：Rong Xiang Xu 出版社：KARGER 发行日期：In 2004
Part 1: AN INEVITABLE OUTCOME OF SCIENTIFIC RESEARCH
This book provides an introduction to the existing therapeutic techniques of local treatment of burns wounds and discusses two therapeutic techniques for treating burns wounds as regards their historical, scientific and technological development. This volume aims at aiding burns medicine researchers and clinicians in developing a correct idea regarding the relative indications of the two therapeutic techniques. It is further hoped that this volume will assist in the elimination of prejudice between different schools as well as to improve the level of the comprehensive burns treatment.
Today, there are only two categories of therapeutic techniques for burns treatment worldwide. One is BRT with MEBO/MEBT, which treats skin burns wounds in such a manner as to achieve both repair and regeneration by creating a wound environment that optimizes the potential of remaining viable tissue. Compared to other treatment protocols, this therapy reduces the rates of scar formation and disability as well as pain suffered and economic burden more than the other technique, which is a surgical skin grafting technique. This second treatment protocol, which aims at treating burns involving whole thickness of the skin and subcutaneous tissues without leaving any viable wound tissue in place, is well known to extract a great physiological price in terms of pain, scarring and residual suffering. It is also far more expensive than BRT with MEBT/MEBO. Prior to the invention of BRT with MEBT/MEBO, widespread utilization of the surgical technique in the treatment of muscle burns and skin burns was acceptable. However, now that scientific studies have demonstrated that BRT with MEBT/MEBO is superior in every way, surgical technique is only a reasonable standard of care in the treatment of skin burns. This conclusion is now a consensus within academic circles worldwide. Surgical burns therapy was born when no other technique could be applied to treat skin burns. Medical researchers and clinicians had been working hard to find a technique for treating skin burns. The emergence of BRT with MEBT/MEBO, represents a blessing to everyone suffering from burns trauma– both the patients and their loyal caregivers. Anyone who has ever cared for burns patients will be relieved and grateful to use BRT with MEBT/MEBO immediately. BRT with MEBT/MEBO is the realization of the dream of all the medical workers and is welcome news to burns patients around the world.
Part 2: AN INEVITABLE OUTCOME OF THE DEVELOPMENT OF MEDICAL SCIENCE
Life science research spans a history of more than 2,500 years. Medical science is only one part of the life science. Medical workers and doctors of successive Chinese dynasties took infinite pains in searching for the key to the door of life science and with it, the ideal methods for controlling diseases. In ancient Greece, Hippocrates established anatomy and surgery, and laid the foundations of modern surgery. Since then, medical workers of the east and the west started using plants and herbs for treating diseases. After the Renaissance, human biochemistry was established, which laid the foundations for the modern treatment strategy of antagonist chemotherapy. Medical sciences developed along with the development of human civilization but the paradigms of medical science were slow to change. In the east, the thinking developed along macro lines of “chi” and patterns of energy flow. Whole plant extracts and consideration of diet predominated in the east whereas in the west, the focus was on more narrow and abstract ideas such as active principles of plants, essential elements and ultimately genetic dynamics. ,
The development of medical treatment methods and drugs lagged behind the development of human civilization. Despite progress in other areas of human endeavor, the methods and materials for enhancing health and saving human life are still limited to two categories, i.e. surgery and internal medicine. The former, while saving lives, compromises viable tissue as well as future anatomical function. The latter, availing itself primarily of chemicals unfavorable to human physiology (e.g. chemotherapy), remains fundamentally antagonistic to tissue health and vitality. Neither modality cooperates with the endogenous vital forces and, therefore, medical workers are ill-equipped to facilitate regeneration of tissues and maintenance of health. Appreciating the present limitations of medical science, all health professionals are encouraged to remain open to new trains of thought, to new methods, techniques and materials, especially those that purport to be working in harmony with the principles of human physiology. The inevitable progress of medical science lies in this direction.
BRT with MEBT/MEBO treats in accordance with the principles of human physiology. The techniques and materials of burns regeneration therapy, by being in compliance with the law of human life, and aiming as it does at maintaining normal physiological functions and physiological activities, becomes a new paradigm for healing. In this book, we publish the theory of this technique, research results and examples of its clinical application. All the data prove that BRT with MEBT/MEBO, with new methodology and a new drug (MEBO), points to a new direction in burns medicine research. The success of BRT with MEBT/MEBO is not only limited to the field of burns medicine but also sheds light upon the nascent research of life medicine itself. Burns wounds are typical traumatic wounds and innovations in burns care are generally applicable in the treatment of traumatic wounds of all kinds. In this book, our data proved that after loss of epidermal tissue, viable epithelial cells in the sweat glands of the subcutaneous tissues can, give the appropriate environment, transform into epithelial stem cells and that these stem cells can, in turn, form new epidermal tissues. This regeneration of epidermal tissue accomplished the first cloning of human tissues and organs in the 21st century. We have demonstrated the inexpensive and potent cloning of a “tissue stem cell”. Therefore, the establishment of BRT with MEBT/MEBO provides the basis for further research in one intriguing aspect of life science - cloning.
Part 3. THE FORMATION OF BURN MEDICAL THERAPY IN 21ST CENTURY
The history of burns therapy as a specialized field of research is less than a hundred years old. While humans have burned themselves since the dawn of time, no systemic intelligent protocols have been established to serve mankind in this regard. Hippocrates did record burns treatment but his methods were not described with any scientific basis. Subsequently, no specialists in burns medicine were formed until after 1930. Research into burns pathogenesis had not produced any impressive methods or materials for treating burns wounds along physiologic lines. Surgical methods saved lives but left patients disfigured and disabled. Surgery, while representing a big step forward, treats the patients while doing nothing to encourage regeneration of the skin. Finally, at the end of the 20th century, Chinese doctors invented burns regenerative medicine and therapy, which offered an entirely new therapy operating in compliance with principles of human physiology. Now, as we enter a new century and while we pause on that threshold, we all share the opportunity to cooperate and combine the best of all approaches from the east and the west. As described above, the technology of the east, i.e. BRT with MEBT/MEBO, should be applied for all burns including muscle burns; while for treating burns in the muscle layer, the technology of the west, i.e. surgical excision and skin grafting therapy, should be applied. As a whole, it can be called integrated east and west burns therapy. In the era of information, any new technology, thinking, method and material when produced, will immediately be known all over the world and the information be shared. New technology is no longer a legendary tree of a doctor that sheds coins when shaken, and the backward technique will no longer be applied to produce tragedy. We believe that in the 21st century, people will make greater progress in the field of burns medicine and the problems will be completely solved as people succeed in the cloning of organs.